Welcome to

orthotreat

Where we revolutionize the field of
bone regeneration through cutting-edge science.

Where we
revolutionize the
field of
bone regeneration through cutting-edge science.

Our Company

OrthoTreat specializes in developing technologies for bone regeneration and various related conditions. We’ve pioneered a novel approach that meticulously oversees the intricate processes of bone regeneration and maintenance, creating a balanced, modulated system with significant clinical impact.

Our Mission

To provide a safe and highly efficient treatment option that accelerates healing, enhances bone quality, and benefits “broken” individuals around the globe.

ModulX®

A dual-drug combination therapy, controlled released and locally injected, with minimal risk factors, integrating:

  • Balanced immune response regulation
  • Sophisticated inflammation control
  • Highly modulated and precisely calibrated growth factor secretion
Image de fond
Hematoma
Reduced osteoclasts differentiation inter alia by RANKL inhibition and by impaired maturation of osteoclast cytoskeleton. Increased osteoblasts differentiation, inter alia by stimulation of BMP-2 expression and increased expression of VEGF.
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Reparative
Stimulation of anti-osteoclastogenic factors (selective CB2 agonist). Restoration of CAT activity; Restoration of SOD activity; Restoration of GPx activity; CB2 stimulation inhibits the release of RANKL.
Exerts anti-inflammatory action via inhibition of various cytokines and chemokines.
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Remodeling
ModulX

Improved and
accelerated healing.

Thereby achieving accelerated, optimal healing throughout the healing period

The Science

Over the last centuries,
bone healing methods
have not undergone any significant improvement.
This fact drove us to believe that a change is possible.
But even more so –
it’s necessary.

Stronger, Smarter & Better Together

Combination of 2 Active Pharmaceutical Ingredients

Stronger, Smarter
& Better Together

Combination of 2 Active Pharmaceutical Ingredients

β-caryophyllene [BCP]

An inflammation-modulating antioxidative agent, a highly selective CB2 agonist approved as GRAS (Generally Recognized as Safe).

Lovastatin [LOV]

A lipid-lowering medication, part of the statin drug class. Positively affects bone healing and regeneration by controlling the expression of important proteins and biochemical pathways.

BCP + LOV

Initiates a favorable cascade
of events, leading to bone regeneration and high-quality bone tissue formation.

Initiates a favorable
cascade of events, leading to bone regeneration and high-quality bone tissue formation.

β-caryophyllene [BCP]

An inflammation-modulating antioxidative agent, a highly selective CB2 agonist approved as GRAS (Generally Recognized as Safe).

Lovastatin [LOV]

A lipid-lowering medication, part of the statin drug class. Positively affects bone healing and regeneration by controlling the expression of important proteins and biochemical pathways.

BCP + LOV

Initiates a favorable cascade
of events, leading to bone regeneration and high-quality bone tissue formation.

Initiates a favorable
cascade of events, leading to bone regeneration and high-quality bone tissue formation.

About Us

Long Story Short

Our genesis entails the coming together of a group of individuals mired by personal medical challenges, coupled with scientific curiosity and strong passion, conviction and belief.

Dr. Marom’s injury during his military service spurred his quest for bone healing advancements as a researcher in a bone laboratory.
Dr. Ehrmann-Barr’s own battle with injury in the service has shaped her character, amplifying a heartfelt commitment to OrthoTreat’s mission, to restore both mobility and quality of life to wounded individuals.

 

Likewise, our CEO, Sahar’s encounter with reoccurring sports injuries, planted the seed
of urgency for a better solution.

United by this common vision and passion, and supported by a strong professional team, the founders embarked on the mission to harness the complex orchestra of physiological processes to create a remedy that enhances and accelerates musculoskeletal recovery. This quest led to a major breakthrough: Our flagship technology, ModulX® a revolutionary drug with an unparalleled potential in the bone-healing segment.

Our genesis entails the coming together of a group of individuals mired by personal medical challenges, coupled with scientific curiosity and strong passion, conviction and belief.

Dr. Marom’s injury during his military service spurred his quest for bone healing advancements as a researcher in a bone laboratory.

Dr. Ehrmann-Barr’s own battle with injury in the service has shaped her character, amplifying a heartfelt commitment to OrthoTreat’s mission, to restore both mobility and quality of life to wounded individuals.

Likewise, our CEO, Sahar’s encounter with reoccurring sports injuries, planted the seed of urgency for a better solution.

United by this common vision and passion, and supported by a strong professional team, the founders embarked on the mission to harness the complex orchestra of physiological processes to create a remedy that enhances and accelerates musculoskeletal recovery.
This quest led to a major breakthrough: Our flagship technology, ModulX® a revolutionary drug with an unparalleled potential in the bone-healing segment.

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